Betty Lou's Seafood & Grill

Nestled in the vibrant heart of San Francisco at 318 Columbus Ave, Betty Lou's Seafood & Grill masterfully blends the freshest coastal flavors with classic Italian and hearty steakhouse influences. This family-friendly restaurant offers a diverse and enticing menu that makes every visit a culinary adventure, whether you’re craving succulent seafood or a robust cut of Creekstone bone-in ribeye steak.

Seafood lovers delight in signature dishes like the Classic Cioppino, a rich, tomato-based seafood stew brimming with generous shrimp, scallops, clams, and mussels—celebrated by diners as one of the best in the city. The Seafood Risotto combines tender clams, mussels, prawns, sea scallops, bay shrimp, and calamari in a creamy, flavorful embrace. Pasta enthusiasts will be captivated by options like the linguine with clams, and the perfectly balanced combo scallop & prawn sauté, crafted with garlic and olive oil to awaken your palate. For those who crave something more indulgent, the half order of linguine pasta offers versatile sauces ranging from rich Alfredo to vibrant basil pesto, promising a dish tailored exactly to your tastes.

The steakhouse side of Betty Lou's also shines, with the Creekstone Bone-In Ribeye embodying juicy, tender perfection that steak connoisseurs appreciate. Appetizers such as Little Neck Clam Shooters and Crab Cakes ensure your meal starts with a burst of flavor. And don’t miss their exquisite desserts — the velvety Tiramisu perfectly rounds out your dining experience.

Step inside Betty Lou’s and you’re greeted by eclectic décor with cozy, breezy vibes reminiscent of a coastal retreat. The atmosphere strikes a delightful balance between casual warmth and refined comfort, making it ideal for family dinners, intimate dates, or lively gatherings with friends. Customer reviews highlight the attentive, knowledgeable staff who deliver fast, efficient service while remaining personable and attentive to detail.

Adding to the experience is a carefully curated wine and beer selection, including bottle options like the crisp Simi Sauvignon Blanc and festive Ruffino Prosecco, perfectly paired with your meal to elevate every bite.

Regulars rave about the consistent quality and fresh ingredients that define Betty Lou's. From the fresh, tender seafood to the perfectly cooked pasta and savory steaks, every dish reveals the chef’s dedication to flavor and authenticity. Whether you’re savoring the Seafood Linguine with Garlic and Olive Oil or indulging in the flavorful Cracked Crab, there’s a genuine care for delivering memorable dining moments that keep guests coming back time and again.

In essence, Betty Lou's Seafood & Grill is not just a restaurant; it’s a celebration of San Francisco’s rich seafood heritage blended with Italian culinary artistry and hearty steakhouse tradition. It’s a place where fresh ocean bounty meets warm hospitality, creating an inviting haven for those who truly appreciate excellent food served with heart.